Actress Helen Mirren has been nominated for three Golden Globes.
The veteran British star will compete against herself for the best mini series actress award, thanks to roles in Prime Suspect: The Final Act and Elizabeth I, and also vyes against fellow Brits Kate Winslet and Judi Dench for the best film actress gong.
The Queen is also in the running for best motion picture drama, best director (for Stephen Frears) and best screenplay (for Peter Morgan).
It has been a good year for the British and Irish at the awards - which celebrate film and television as well as hosting separate categories for drama and comedy or musicals.
Peter O'Toole has a best actor nomination for his role alongside fellow veteran Leslie Phillips in comedy drama Venus, while in comedy or musical best acting category, Sacha Baron Cohen and Chiwetel Ejiofor are both up for the prize, for Borat and Kinky Boots respectively.
Netting the most nominations, however, was Alejandro Gonzalez Inarritu's Babel. Known for his multi-layered plots (Amores Perros, 21 Grams) Babel is in a similar vein, tracking four stories across three countries.
The film has picked up nods for best motion picture, best director, best actress (with nominations for Adriana Barraza and Rinko Kikuchi), best actor (for Brad Pitt), best screenplay (for Guillermo Arriaga) and best original score (for Gustavo Santaolalla).
Also nominated for multiple awards was Martin Scorcese's The Departed - in the running for best drama motion picture drama, best drama actor (Leonardo DiCaprio), supporting actor (for both Mark Wahlberg and Jack Nicholson), best screenplay (William Monahan) and best director.
Little Children also faired well. In addition to its nomination for Winslet, it is also in the running for best drama picture and best screenplay (for Todd Filed and Tom Perrotta).
This year also sees the introduction of a new category for best animated feature, with Cars, Happy Feet and Monster House all aiming for the top.
Several big-screen names are also competing in the television segment of the awards, including Toni Colette and Chiwetel Ejiofor - for their roles in BBC/HBO collaboration Tsunami, The Aftermath - Jeremy Irons (Elizabeth I), Thomas Hayden Church (Broken Trail), Bill Nighy (Gideon's Daughter) and Ben Kingsley and Annette Bening for fact-based drama Mrs Harris.
The winners will be announced at a ceremony in LA on January 15.
The full list of nominations is:
Best Motion Picture - Drama
Babel
Bobby
The Departed
Little Children
The Queen
Best Performance By An Actress In A Motion Picture - Drama
Penelope Cruz - Volver
Judi Dench - Notes On A Scandal
Maggie Gyllenhaal - Sherrybaby
Helen Mirren - The Queen
Kate Winslet - Little Children
Best Performance By An Actor In A Motion Picture - Drama
Leonardo DiCaprio - Blood Diamond
Leonardo DiCaprio - The Departed
Peter O'Toole - Venus
Will Smith - The Pursuit Of Happyness
Forest Whitaker - The Last King Of Scotland
Best Motion Picture - Comedy Or Musical
Borat: Cultural Learnings Of America For Make Benefit Glorious Nation Of Kazakhstan
The Devil Wears Prada
Dreamgirls
Little Miss Sunshine
Thank You For Smoking
Best Performance By An Actress In A Motion Picture - Comedy Or Musical
Annette Bening - Running With Scissors
Little Miss Sunshine
Beyonce Knowles - Dreamgirls
Meryl Streep - The Devil Wears Prada
Renee Zellweger - Miss Potter
Best Performance By An Actor In A Motion Picture - Comedy Or Musical
Sacha Baron Cohen - Borat: Cultural Learnings Of America For Make Benefit Glorious Nation Of Kazakhstan
Johnny Depp - Pirates Of The Caribbean: Dead Man's Chest
Aaron Eckhart - Thank You For Smoking
Chiwetel Ejiofor - Kinky Boots
Will Ferrell - Stranger Than Fiction
Best Animated Feature Film
Cars
Happy Feet
Monster House
Best Foreign Language Film
Apocalypto (USA)
Letters From Iwo Jima (USA/Japan)
The Lives Of Others (Germany)
Pan's Labyrinth (Mexico/Spain/USA)
Volver (Spain)
Best Performance By An Actress In A Supporting Role In A Motion Picture
Adriana Barraza - Babel
Cate Blanchett - Notes On A Scandal
Emily Blunt - The Devil Wears Prada
Jennifer Hudson - Dreamgirls
Rinko Kikuchi - Babel
Best Performance By An Actor In A Supporting Role In A Motion Picture
Ben Affleck - Hollywoodland
Eddie Murphy - Dreamgirls
Jack Nicholson - The Departed
Brad Pitt - Babel
Mark Wahlberg - The Departed
Best Director - Motion Picture
Clint Eastwood - Flags Of Our Fathers
Clint Eastwood - Letters From Iwo Jima
Stephen Frears - The Queen
Alejandro Gonzalez Inarritu - Babel
Martin Scorsese - The Departed
Best Screenplay - Motion Picture
Guillermo Arriaga - Babel
Todd Field & Tom Perrotta - Little Children
Patrick Marber - Notes On A Scandal
William Monahan - The Departed
Peter Morgan - The Queen
Best Original Score - Motion Picture
Alexandre Desplat - The Painted Veil
Clint Mansell - The Fountain
Gustavo Santaolalla - Babel
Carlo Siliotto - Nomad
Hans Zimmer - The Da Vinci Code
Best Original Song - Motion Picture
"A Father's Way" - The Pursuit Of Happyness
Music By: Seal And Christopher Bruce
Lyrics By: Seal
"Listen" - Dreamgirls
Music & Lyrics By: Henry Krieger, Anne Preven, Scott Cutler And Beyonce Knowles
"Never Gonna Break My Faith" - Bobby
Music & Lyrics By: Bryan Adams, Eliot Kennedy And Andrea Remanda
"The Song Of The Heart" - Happy Feet
Music & Lyrics By: Prince Rogers Nelson
"Try Not To Remember" - Home Of The Brave
Music & Lyrics By: Sheryl Crow
Best Television Series - Drama
24
Big Love
Grey's Anatomy
Heroes
Lost
Best Performance By An Actress In A Television Series - Drama
Patricia Arquette - Medium
Edie Falco - The Sopranos
Evangeline Lilly - Lost
Ellen Pompeo - Grey's Anatomy
Kyra Sedgwick - The Closer
Best Performance By An Actor In A Television Series - Drama
Patrick Dempsey - Grey's Anatomy
Michael C. Hall - Dexter
Hugh Laurie - House
Bill Paxton - Big Love
Kiefer Sutherland - 24
Best Television Series - Comedy Or Musical
Desperate Housewives
Entourage
The Office
Ugly Betty
Weeds
Best Performance By An Actress In A Television Series - Comedy Or Musical
Marcia Cross - Desperate Housewives
America Ferrera - Ugly Betty
Felicity Huffman - Desperate Housewives
Julia Louis-Dreyfus - The New Adventures Of Old Christine
Mary-Louise Parker - Weeds
Best Performance By An Actor In A Television Series - Comedy Or Musical
Alec Baldwin - 30 Rock
Zach Braff - Scrubs
Steve Carell - The Office
Jason Lee - My Name Is Earl
Tony Shalhoub - Monk
Best Mini-Series Or Motion Picture Made For Television
Bleak House
Broken Trail
Elizabeth I
Mrs. Harris
Prime Suspect: The Final Act
Best Performance By An Actor In A Mini-Series Or Motion Picture Made For Television
Andre Braugher - Thief
Robert Duvall - Broken Trail
Michael Ealy - Sleeper Cell: American Terror
Chiwetel Ejiofor - Tsunami, The Aftermath
Ben Kingsley - Mrs. Harris
Bill Nighy - Gideon's Daughter
Matthew Perry - The Ron Clark Story
Best Performance By An Actress In A Supporting Role In A Series, Mini-Series Or Motion Picture Made For Television
Emily Blunt - Gideon's Daughter
Toni Collette - Tsunami, The Aftermath
Katherine Heigl - Grey's Anatomy
Sarah Paulson - Studio 60 On The Sunset Strip
Elizabeth Perkins - Weeds
Best Performance By An Actor In A Supporting Role In A Series, Mini-Series Or Motion Picture Made For Television
Thomas Haden Church - Broken Trail
Jeremy Irons - Elizabeth I
Justin Kirk - Weeds
Masi Oka - Heroes
Jeremy Piven - Entourage